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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAPK1 All Species: 27.58
Human Site: S975 Identified Species: 60.67
UniProt: P53355 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53355 NP_004929.2 1430 160073 S975 K I I S T L P S W R K L N G P
Chimpanzee Pan troglodytes XP_001140200 1430 160025 S975 K I I S T L P S W R K L N G P
Rhesus Macaque Macaca mulatta XP_001084634 1430 160024 S975 K I I S T L P S W R K L N G P
Dog Lupus familis XP_541259 1430 159848 S975 K I I S T L P S W R K L N G P
Cat Felis silvestris
Mouse Mus musculus Q80YE7 1442 161423 S975 K I I S T L P S W R K L N G P
Rat Rattus norvegicus O88764 448 51431 P50 F I K K R R L P S S R R G V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026784 974 109076 H576 F V D F Q D R H G N T P L H V
Frog Xenopus laevis NP_001086727 1427 159871 S972 K V M S T L P S W R K Q N G P
Zebra Danio Brachydanio rerio NP_001093460 1439 159594 S972 K L L S T L P S W R K L N G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_490840 1425 158950 L970 T V V N H L N L V R K K H A N
Sea Urchin Strong. purpuratus XP_780774 1084 119703 S685 G E V Q C F G S E L L Q E V I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.3 95.5 N.A. 94.3 24.2 N.A. N.A. 60.7 86 74.7 N.A. N.A. N.A. 34.5 29.5
Protein Similarity: 100 99.9 99.7 97.9 N.A. 97.5 28.8 N.A. N.A. 65.8 93.8 87.2 N.A. N.A. N.A. 54.4 45.9
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. N.A. 0 80 86.6 N.A. N.A. N.A. 20 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. N.A. 6.6 93.3 100 N.A. N.A. N.A. 46.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 10 0 0 0 10 0 0 % E
% Phe: 19 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 10 0 10 0 0 0 10 64 0 % G
% His: 0 0 0 0 10 0 0 10 0 0 0 0 10 10 0 % H
% Ile: 0 55 46 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 64 0 10 10 0 0 0 0 0 0 73 10 0 0 0 % K
% Leu: 0 10 10 0 0 73 10 10 0 10 10 55 10 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 10 0 0 10 0 0 64 0 10 % N
% Pro: 0 0 0 0 0 0 64 10 0 0 0 10 0 0 64 % P
% Gln: 0 0 0 10 10 0 0 0 0 0 0 19 0 0 0 % Q
% Arg: 0 0 0 0 10 10 10 0 0 73 10 10 0 0 0 % R
% Ser: 0 0 0 64 0 0 0 73 10 10 0 0 0 0 10 % S
% Thr: 10 0 0 0 64 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 28 19 0 0 0 0 0 10 0 0 0 0 19 10 % V
% Trp: 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _